УДК 577.3
Fluorescence spectroscopy (FS) has recently become more common in clinical medicine. However, there are still many unresolved issues related to the methodology and implementation of instruments with this technology.
Here we provide evidence that the level of blood volume in tissue impacts FS data with a significant inverse correlation. The effects of various physiological (different content of skin melanin) and technical factors on the measurement results were additionally studied.
The data on the variability of the measurement results in FS should be considered when interpreting the diagnostic parameters, as well as when developing new algorithms for data processing and FS devices.